knee cycle

We’ve updated our website research page and will be adding new analysis by Dr. Bunyak regularly. For all of you interested in the science of regenerative healing, visit the BOUNDLESS Research page here.

Dr. Bunyak notes especially these four recent studies:

Effects of bone marrow aspirate concentrate and platelet-rich plasma on patients with partial tear of the rotator cuff tendon
Article Here
(Sang, Jun Kim, et. al., 1/3/2018)
There is building evidence for the efficacy of regenerative therapies in rotator cuff tear repair. In this study, bone marrow/PRP was compared to exercise control (also known to have a regenerative effect) for partial thickness rotator cuff tears–both groups had a decrease in size of tear (3 months) and the BM/PRP group had improvement in pain/function above exercise. Pre-published date supports these findings–not only partial thickness, but full thickness tears are healing with the help of PRP, bone marrow, and matrix injections.

Female hormonal factors and osteoarthritis of the knee, hip, and hand: a narrative review
Abstract Here
(Hussain, S.M., 1/30/2018)
This study looks at the effect of female hormones on the development of arthritis. Hormone effects on healing have been shown in multiple studies, and hormone replacement has been shown to improve healing and regeneration of muscle and tendinous tissue. Whether to include hormone replacement, even short term, in the regenerative plan is an individual decision that should be discussed as part of a personalized regeneration plan.

The effect of impactful papers on clinical practice in the US: Corticosteroid injection for patients with lateral epicondylitis
Article Here
(Fujihara, Y., 1/12/2018)
This great article proves that few physicians are reading the research or incorporating it in their practice. This study shows that most orthopedic surgeons and other physicians have continued to use steroid injections for tennis elbow, despite studies proving that (at best) they don’t work and (at worst) are degenerative. Similarly, steroid injections continue to be used in arthritis despite evidence that they have no significant effect on pain and a damaging effect on cartilage. In fact, only 20% of orthopedic procedures are supported by current research. This common practice inertia can also be argued to limit the incorporation of new therapies, such as PRP and other regenerative injections, even though high quality evidence now exists for their use.

Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis
Article Here
(Liu, X., 10/17/2017)
This review of supplements for arthritis looks at which supplements may significantly help with symptoms and which are likely a waste of money.